John Mascarenhas, M.D.

Dr. John Mascarenhas is Professor of Medicine at the Icahn School of Medicine at Mount Sinai. He directs the Adult Leukemia Program and leads clinical investigation within the Myeloproliferative Disorders Program. As a clinical investigator in malignant hematology with a focus on translational research involving myeloproliferative neoplasms (MPNs) and evolution to acute myeloid leukemia (AML), Dr. Mascarenhas evaluates rationale-based novel therapies for patients with MPNs and AML.

He has served as PI or Study Chair of multiple investigator-initiated and industry-sponsored early- and late-phase clinical trials evaluating innovative approaches to the treatment of MPNs and AML. Additionally, he holds multiple administrative roles at Mount Sinai—he is Chair of the Leukemia Disease Management Team, Co-Chair of the Hematologic Malignancy Disease Focus Group, and a full member of the Mount Sinai Tisch Cancer Center Protocol and Review Monitoring Committee.